The clinical knowledge you need, when you need it

Guidelines, drug information and medical literature

For clinical questions, Mosaic draws on medical evidence and links the answer directly to the underlying sources.

AWMFGuidelines
DEGAMGuidelines
ESCGuidelines
EMADrug information
NEJMJournal
The LancetJournal
CochraneSystematic reviews
PubMedMedical literature

Medical knowledge at hand

Guidelines and scientific evidence for clinical decision-making, ready when you need them.

Lipoprotein(a) has never been measured; once, with the next draw, because her father had a heart attack at 58 Eur Heart J.

References4

1.2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.European Heart Journal. 2020;41:111-188. Mach F, Baigent C, Catapano AL, et al.Guideline
2.2024 ESC Guidelines for the management of elevated blood pressure and hypertension.European Heart Journal. 2024;45:3912-4018. McEvoy JW, McCarthy CP, Bruno RM, et al.Guideline
3.Hausärztliche Risikoberatung zur kardiovaskulären Prävention. S3-Leitlinie.AWMF-Register 053-024. DEGAM, Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin.Guideline
4.Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174 000 participants in 27 randomised trials.The Lancet. 2015;385:1397-1405. Cholesterol Treatment Trialists’ Collaboration.Trial

Every response sourced and cited

Jump straight to the source. Every answer points to the record and the evidence it draws on.

What should I consider next for her, and why?

A statin rechallenge comes first: atorvastatin 10 mg in the evening, LDL target below 100 mg/dl, lipids, ALT and CK after eight weeks ESC DEGAM. Across 27 randomised studies, lowering LDL by 39 mg/dl cut major vascular events by about a fifth, also at low risk Lancet Lab 08.05.2026.

The muscle aches of 2024 matter more than any interaction: CK was 210 U/l then and 96 U/l in May Visit 14.03.2024. Start low, and ask on day 3, 7 and 14.

Blood pressure is above the target of 120 to 129 systolic with a home mean of 136/86; ramipril to 10 mg, potassium and creatinine after two weeks ESC BP log 15.09.2026.

Lipoprotein(a) has never been measured; once, with the next draw, because her father had a heart attack at 58 Eur Heart J.

Reference1 of 4, see all

1.2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk.

European Heart Journal. 2020;41:111-188. Mach F, Baigent C, Catapano AL, et al.

LDL cholesterol goals by risk category: below 116 mg/dl at low risk, below 100 mg/dl at moderate risk, below 70 mg/dl at high risk. Statins first, ezetimibe second; the checks of ALT and CK after the start are defined.

The full record behind the answer

Ask anything about the record. Diagnoses, history, condition and treatment inform the answer.

What should I consider next for her, and why?

A statin rechallenge comes first: atorvastatin 10 mg in the evening, LDL target below 100 mg/dl, lipids, ALT and CK after eight weeks ESC DEGAM. Across 27 randomised studies, lowering LDL by 39 mg/dl cut major vascular events by about a fifth, also at low risk Lancet Lab 08.05.2026.

The muscle aches of 2024 matter more than any interaction: CK was 210 U/l then and 96 U/l in May Visit 14.03.2024. Start low, and ask on day 3, 7 and 14.

Blood pressure is above the target of 120 to 129 systolic with a home mean of 136/86; ramipril to 10 mg, potassium and creatinine after two weeks ESC BP log 15.09.2026.

Lipoprotein(a) has never been measured; once, with the next draw, because her father had a heart attack at 58 Eur Heart J.

What you can ask Mosaic

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The patient record and medical knowledge in one place

	Mosaic	ChatGPT
Patient record	Takes the documented course into account	Knows only what you paste in
Clinical questions	In natural language	In natural language
Evidence	Guidelines, drug information and medical literature	General knowledge from the web
Traceability	Record entries and medical sources right at the answer	Sources on request, not consistently cited
Documentation	Drafts based on the existing context	Drafts from the text you enter
Clinical responsibility	Review and decision stay with the physician	Stays with the physician

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9:41

Anna Keller, 47, Hypertension

Summarize her history in five lines, with the sources

Answered on 29 September 2026, Finished thinking

Arterial hypertension since September 2023 on ramipril 5 mg, home mean 136/86 last week BP log 15.09.2026. LDL 162 mg/dl, simvastatin stopped in March 2024 for muscle aches Visit 14.03.2024, above the goal of the guideline ESC 2021 DEGAM.

Open in the chart: lipoprotein(a) never measured Findings.

Sources4›

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