Take-home · Petra S., 51
Take-home

Transdermal estradiol: how it works for you

Petra S., 51 · 18 September 2026 · Shared with the patient, 18 September 2026, opened

Why through the skin

Because of your migraine with aura we chose the gel instead of tablets. Oestrogen taken as a tablet passes through the liver and can raise the risk of a clot; through the skin it does not.

How to use it

One pump on the inner arm every morning, spread it and let it dry before you dress. Progesterone every evening; it also helps your sleep.

What to expect

  • Flushes ease within two to four weeks
  • Tender breasts or spotting in the first weeks are commonThey usually settle. Tell us if they do not.
  • Call us if your migraine with aura returns

Next

  • 25 Sep 2026Gynaecological check-up
  • 18 Dec 2026Follow-up

Sources

S3 guideline, AWMF 015-062

Written from the consultation and the S3 guideline, in plain language, shared under the physician's name.